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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
CENPE
All Species:
15.15
Human Site:
T475
Identified Species:
27.78
UniProt:
Q02224
Number Species:
12
Phosphosite Substitution
Charge Score:
0.08
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q02224
NP_001804.2
2701
316415
T475
E
S
D
V
F
S
N
T
L
D
T
L
S
E
I
Chimpanzee
Pan troglodytes
XP_001170168
2701
316707
T475
E
S
D
V
F
S
N
T
L
D
T
L
S
E
I
Rhesus Macaque
Macaca mulatta
XP_001110512
2701
316828
T475
E
S
D
V
F
S
N
T
L
D
T
L
N
E
I
Dog
Lupus familis
XP_852631
1216
141588
Cat
Felis silvestris
Mouse
Mus musculus
Q6RT24
2474
286506
T478
E
F
E
M
L
N
N
T
L
E
S
L
A
E
V
Rat
Rattus norvegicus
Q7TSP2
1385
159522
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
XP_420670
2150
248600
E186
M
E
W
I
R
K
G
E
K
N
R
H
Y
G
E
Frog
Xenopus laevis
NP_001080954
2954
339950
V617
Q
T
D
V
E
K
E
V
V
R
K
E
M
S
V
Zebra Danio
Brachydanio rerio
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
NP_524993
2013
231091
V49
E
P
Y
V
F
D
Y
V
F
D
E
G
A
S
N
Honey Bee
Apis mellifera
XP_001121311
1418
164919
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_781622
2537
290578
S470
F
I
S
M
S
S
G
S
V
S
S
I
S
S
D
Poplar Tree
Populus trichocarpa
XP_002308893
1247
142380
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
NP_187629
1348
152938
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
98.7
95.7
37.8
N.A.
60.5
21.2
N.A.
N.A.
37.1
31
N.A.
N.A.
26.1
24.8
N.A.
25.5
Protein Similarity:
100
99.2
98
42
N.A.
75
35.7
N.A.
N.A.
55
52.2
N.A.
N.A.
45.6
37.8
N.A.
48.8
P-Site Identity:
100
100
93.3
0
N.A.
40
0
N.A.
N.A.
0
13.3
N.A.
N.A.
26.6
0
N.A.
13.3
P-Site Similarity:
100
100
100
0
N.A.
86.6
0
N.A.
N.A.
13.3
40
N.A.
N.A.
33.3
0
N.A.
46.6
Percent
Protein Identity:
23.9
N.A.
N.A.
24.9
N.A.
N.A.
Protein Similarity:
34.6
N.A.
N.A.
37.6
N.A.
N.A.
P-Site Identity:
0
N.A.
N.A.
0
N.A.
N.A.
P-Site Similarity:
0
N.A.
N.A.
0
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
0
0
0
0
0
0
0
0
16
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
31
0
0
8
0
0
0
31
0
0
0
0
8
% D
% Glu:
39
8
8
0
8
0
8
8
0
8
8
8
0
31
8
% E
% Phe:
8
8
0
0
31
0
0
0
8
0
0
0
0
0
0
% F
% Gly:
0
0
0
0
0
0
16
0
0
0
0
8
0
8
0
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
8
0
0
0
% H
% Ile:
0
8
0
8
0
0
0
0
0
0
0
8
0
0
24
% I
% Lys:
0
0
0
0
0
16
0
0
8
0
8
0
0
0
0
% K
% Leu:
0
0
0
0
8
0
0
0
31
0
0
31
0
0
0
% L
% Met:
8
0
0
16
0
0
0
0
0
0
0
0
8
0
0
% M
% Asn:
0
0
0
0
0
8
31
0
0
8
0
0
8
0
8
% N
% Pro:
0
8
0
0
0
0
0
0
0
0
0
0
0
0
0
% P
% Gln:
8
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% Q
% Arg:
0
0
0
0
8
0
0
0
0
8
8
0
0
0
0
% R
% Ser:
0
24
8
0
8
31
0
8
0
8
16
0
24
24
0
% S
% Thr:
0
8
0
0
0
0
0
31
0
0
24
0
0
0
0
% T
% Val:
0
0
0
39
0
0
0
16
16
0
0
0
0
0
16
% V
% Trp:
0
0
8
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
8
0
0
0
8
0
0
0
0
0
8
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _